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Are you 40+ and finding that things get to you more than they used to? You're not alone. During perimenopause and menopause, many women notice a shift in how they respond to stress. And because the brain and skin are closely connected, what happens on the inside can show up on the outside. Here's what's behind it, plus what you can do to feel (and look) better.
It's usually a mix of a few things:
When estrogen and progesterone levels fluctuate, your mood and stress response can be affected. Estrogen interacts with serotonin and other neurotransmitters, while progesterone can have a calming effect. During perimenopause, both rise and fall unpredictably, which can impact how you respond to stress. It's not that you've suddenly become more sensitive for no reason: your body is adjusting to these hormonal shifts.
We talk a lot about stress, but what exactly is it? In simple terms, it's your body's response to anything it perceives as a threat or additional demand: an exam, a conflict, a bad night's sleep. It's not just "in your head." Stress triggers a physiological response that can affect your entire system.
That's where cortisol comes in. When your brain detects an alarm signal, your body releases cortisol. It has a bad reputation, but in the right amount, it's essential: it helps make energy available and prepares your body to respond. The problem isn't cortisol itself, but what happens when that alarm stays switched on for too long. If stress becomes chronic, cortisol can remain elevated, affecting other systems in the body. Including your skin.
Hormonal changes, stress, and poor sleep can temporarily affect concentration and memory during the menopause transition. Sound familiar? Forgetting why you walked into a room, losing your train of thought, or having a word on the tip of your tongue can all be common during this stage. And while frustrating, these changes are often temporary.
Your skin doesn't exist in isolation from the rest of your body, and when cortisol remains elevated for too long, skin function can be affected: the skin barrier may take longer to recover, lose hydration more easily, and become more reactive. The result:
On top of that, the drop in estrogen that comes with menopause can contribute to the loss of collagen, firmness, and elasticity. It's a double whammy: hormonal changes on one side, sustained stress on the other.
Self-care doesn't need to become one more thing on your to-do list. Small, consistent habits can make a real difference:
If stress, anxiety, or low mood interferes with your daily life, consider talking to a professional.
To support your skin through the changes of menopause, we created Essential Shock (R)Evolution, a collagen boost designed to help improve firmness, hydration, and suppleness while smoothing the appearance of wrinkles.
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⋅ Gordon JL, Girdler SS, Meltzer-Brody SE, et al. Ovarian hormone fluctuation, neurosteroids, and HPA axis dysregulation in perimenopausal depression: a novel heuristic model. American Journal of Psychiatry. 2015;172(3):227–236. PubMed
⋅ Altemus M, Rao B, Dhabhar FS, Ding W, Granstein RD. Stress-induced changes in skin barrier function in healthy women. Journal of Investigative Dermatology. 2001;117(2):309–317. PubMed
⋅ Chen Y, Lyga J. Brain-skin connection: stress, inflammation and skin aging. Inflammation & Allergy—Drug Targets. 2014;13(3):177–190. PubMed
⋅ Faleschini S, Tiemeier H, Rifas-Shiman SL, et al. Longitudinal associations of psychosocial stressors with menopausal symptoms and well-being among women in midlife. Menopause. 2022;29(11):1247–1253. PubMed
⋅ Zouboulis CC, Blume-Peytavi U, Kosmadaki M, et al. Skin, hair and beyond: the impact of menopause. Climacteric. 2022;25(5):434–442. PubMed
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